Immunotherapy – 2074. Tolerability of sublingual immunotherapy with tropical mite allergen vaccines using different dosing schedules in asthmatic children
نویسندگان
چکیده
Background Immunotherapy with mite allergens is effective both in rhinitis and asthma. However, injection immunotherapy carries a high risk of systemic adverse events, so, the sublingual route (SLIT) is being used more frequently. Efficacy of SLIT in asthma has been widely studied, however, in Cuba, the therapeutic effect of mite vaccines of Dermatophagoides pteronyssinus (Dp), D.siboney (Ds) and Blomia tropicalis(Bt) has been demonstrated only in adults, but not children. This aim is to determinate adherence and tolerability of SLIT with mite allergen vaccines using different treatment schedules in asthmatic children.
منابع مشابه
Safety of sublingual immunotherapy for asthma with standardized house dust mite vaccines in a tropical setting: Results of a nation-wide pharmacovigilance study
Background Pharmacovigilance studies are helpful to follow the use of allergen immunotherapy in clinical practice. Industrially manufactured allergen vaccines (VALERGEN) of three mite species (including the tropical species Dermatophagoides siboney and Blomia tropicalis) have been recently introduced country-wide in Cuba for asthma treatment. To assess the safety and efficacy of allergen immuno...
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